[ituh], from 1st link, Introduction, "Smoking, hypertension, dyslipidemia, and diabetes mellitus are main
risk factors for cardiovascular disease1. Smoking cessation is the most effective lifestyle intervention for prevention of cardiovascular and neoplastic diseases, as well as chronic obstructive pulmonary disease, and smoking cessation treatments improve the control of autoimmune inflammatory diseases2. Impaired endothelial function, arterial stiffness, increased inflammation, lipid alteration, and prothrombotic factors are associated with smoking and appear to initiate as well as accelerate the atherothrombotic process, eventually leading to cardiovascular events3.
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